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Ceramide NP, AP, EOP: The Ultimate Guide to the Best Ceramides for Skin Barrier Repair

You might have heard that ceramides are essential to a healthy, strong skin barrier. But when you start skimming ingredient lists, you’ll soon encounter an alphabet soup of ingredients with similar-looking names like ceramide NP, ceramide AP, cramide EOP, etc. It can be pretty confusing! So in this blog, the chemists dive into what these letters all mean and if there’s a best one that you have to have in your skincare. Listen to the Ceramides Chat on the Chemist Confessions Podcast What are C...

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Hypochlorous Acid for Skin: Miracle or Marketing?

Hypochlorous acid (HOCl) for skin is the latest "miracle ingredient" buzzing in the skincare world. Fans tout its transformative HOCl benefits from scar healing to acne. But what is this molecule, how does it work, and is it actually deserving of all the hype? Let’s break down everything the chemists think you should know before adding a Hypochlorous acid spray to your routine. What is Hypochlorous Acid? HOCl is a weak acid and potent pro-oxidant that our body naturally produces as a defense ...

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Do you put sunscreen on before or after makeup? The Chemists’ Guide to Sunscreen Application

The hotter days are here and that means you’re probably getting bombarded with sunscreen content. Sadly, more often than not, you’ll see more scary misinformation, conflicting recommendations than actual helpful guidelines on just what to do to protect yourself from the sun. Fear not! We’re here to help tackle all of your sunscreen application questions with evidence-based suggestions. In this guide, we’ll cover the correct sunscreen application amount, just how should you layer foundation wi...

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Reedle Shot Deep Dive! Science of Spicules in Skincare

Spicules. You might have heard this term or the trendy VT Reedle Shot products that tout spicule technology on social media recently. But what exactly are they? Don’t worry! We gotchu. The chemists are taking a deep dive into what spicules are, how they function in topical applications in theory, any clinical testing evidence, whether you should be considering adding spicules to your skincare routine, and just how to properly use VT Reedle Shots. What Are Spicules? Spicules are structural ske...

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PDRN Skincare: Hype vs. Reality

New skincare science is as alluring as it is mysterious. It can often be hard to distinguish between hype and science. But worry not! Let the chemists dissect everything for you. Today, we’re tackling PDRNv—van ingredient that’s been making waves in the beauty world. But what exactly is PDRN, and does it deserve a spot in your routine? Let’s break it down. What is PDRN? PDRN, or polydeoxyribonucleotide, are simply DNA fragments ranging from 50 to 1500 kDa. The concept of using PDRN for therap...

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RESULTS SUMMARY FOR OUR 2024 30-FOR-30 SUNSCREEN CHALLENGE

In celebration of summer, we decided to test 30 different sunscreens over 30 days to see how these applied, how they held up over time, and even how they wash off. Please head to our TikTok and Instagram channel if you want to see the visuals. Otherwise here’s the running list of sunscreens we’ve tried, our rating, and why: *To help readers learn more about products showcased in this challenge, we built out and organized these results in Shop My Shelf. We do receive a small commission for usi...

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Results Summary for our 2023 30-for-30 Sunscreen Challenge

In celebration of summer, we decided to test 30 different sunscreens over 30 days to see how these applied, how they held up over time, and even how they wash off. Please head to our TikTok and Instagram channel if you want to see the visuals. Otherwise here’s the running list of sunscreens we’ve tried, our rating, and why: *To help readers learn more about products showcased in this challenge, we built out and organized these results in Shop My Shelf. We do receive a small commission for usi...

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Which Vitamin C Derivative is the Best For My Skin?

We have talked about the science behind vitamin C skincare, we have even tested a bunch of CE Ferulic dupes - yet there’s still more for us to cover in the vitamin C serum landscape. Vitamin C is actually a whole family of related molecules that all behave slightly differently. The OG vitamin C with the glitzy skin benefits that you often hear of is L-ascorbic acid. But since ascorbic acid is notoriously unstable in the presence of light, water, and air, many have turned to derivative compoun...

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Retinal - Is it Better Than Retinol?

Retinaldehyde or retinal (with an A!) has become the latest, buzz-worthy retinoid on the market. Many seasoned retinoid users are honing in on the fact that in the process of retinoic acid synthesis, retinal would be the more efficient (aka more potent) cosmetic retinoid compared to retinol in getting those sweet anti-aging benefits. You might even hear retinal claims such as “10x more effective than retinol” or even “tretinoin strength without the tretinoin irritation.” Bold claims! While re...

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Azelaic, Tranexamic, Kojic Acid... The Chemists' Best Hyperpigmentation Ingredients Guide

Uneven skin tone, post-inflammatory hyperpigmentation, dark spots, sun spots, acne scars, melasma… it doesn’t matter what type of hyperpigmentation concern you have, this is one of THE most stubborn skin concerns to tackle. This is an arena where you don’t just need one single BEST ingredient, but a whole family of clinically validated hyperpigmentation-busting ingredients. So let’s go through some of the ingredients you’ll likely come across in your quest to brighten, even skin tone, and tac...

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5 Skinceuticals Vitamin C Dupes Put to the Test!

If you’re unfamiliar with the term “Vitamin C Dupe”, it’s a category of ascorbic acid serums that sprouted from the painful price point of the original ascorbic acid serum, Skinceuticals CE Ferulic. As a result, a whole new category of ascorbic acid serums popped up on the market and these products come in all sorts of packaging, price points, and ascorbic acid percentages. For a while, we were holding out on looking at this category because it felt messy. Let’s just say, we knew how much of ...

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