LÉ Blog
Adapalene vs Retinol: Which Is Better For Your Skin?
Adapalene and retinol are two of the most talked-about ingredients in modern skincare, and for good reason. Both retinoids claim smoother texture, fewer breakouts, and a visible boost in skin clarity. Yet for many, figuring out which one belongs in their routine feels more like decoding a chemistry exam than building a skincare lineup. At Chemist Confessions, we offer a scientist’s perspective to the confusion, cutting through marketing myths to explain what these actives actually do. Adapale...
Read moreCan You Use Niacinamide And Vitamin C? A Chemist's Opinion
If you’ve ever stood in front of your skincare shelf, asking yourself, 'Can you use niacinamide with vitamin C?' you’re in good company. The mix-or-don’t-mix debate has been floating around for years, often leaving people more confused than confident. Some say these ingredients cancel each other out. Others claim they work beautifully together. Here’s what we know: both niacinamide and vitamin C are backed by solid research and show up in some of the most effective skincare formulas today. So...
Read moreCan You Use Niacinamide With Retinol? What Scientists Say
Mixing active ingredients in your skincare routine can feel like a chemistry class no one prepared you for. Niacinamide and retinol are both popular skincare ingredients, but using them together in the same routine raises several questions. Is it too harsh? Will they cancel each other out? Should you be worried about irritation? It’s completely normal to feel unsure. The good news is, you don’t have to pick sides. When used thoughtfully, niacinamide and retinol can actually complement each ot...
Read moreEverything you need to know about silymarin in skincare
If you’ve spotted silymarin or milk thistle extract on a skincare label and found yourself wondering what it actually does, you’re in the right place. This plant-derived compound is gaining attention in modern formulas for its ability to calm, protect, and support the skin without adding complexity to your routine. There’s real interest right now in milk thistle benefits for skin, especially among people who want a more thoughtful, ingredient-aware approach to skincare. From its antioxidant b...
Read moreWhat Are Ceramides? Their Role In Strengthening And Protecting Your Skin
You’re standing in the skincare aisle, scanning labels, and there it is again: ceramides. They show up in moisturizers, serums, and creams of every kind, usually with big promises about being the must-have ingredient for barrier care. But what are ceramides, exactly? In short, ceramides are a group of lipid molecules that are naturally found in the skin’s lipid matrix. Acting as part of your skin’s frontline defense system: In contributing to the health of your lipid matrix, they help lock in...
Read moreWhat Is Retinol Purging? How To Identify And Manage Skin Reactions
Let’s set the record straight: Retinol purging isn’t your skin “rejecting” a product. It’s more like a sped-up reveal of breakouts that were already in your skin’s pipeline, triggered by the introduction of retinoids accelerate cell turnover. But not every flare-up is a purge. Sometimes, it’s just plain old irritation or a bad match. Being able to tell the difference helps you stick with the right plan or switch gears when needed. The chemists have spent years getting up close and personal wi...
Read moreIs Ethyl Ascorbic Acid a Worthy Vitamin C Derivative?
3-o-ethyl ascorbic acid, or “ethylated ascorbic acid” is a vitamin C derivative that’s risen quickly in the popularity ranks in recent years. But just because it’s a structural cousin of hte famed ascorbic acid doesn’t automatically mean that it’s going to delivery all those vitamin C skin benefits you’re looking for. So let’s break down the science - chemist style - and get the the bottom of just whether or not ethyl ascorbic acid is the stable, gentle, age-prevention superstar worthy of rep...
Read moreIs Ectoin the New Niacinamide?
When it comes to trending skincare ingredients, ectoin isn’t exactly a household name. But recently, this ingredient has caught the attention of many clinical skincare brands. It has many interesting properties, particularly for skin barrier support and hydration. In fact, the early data has some people touting that this may just be the “new age niacinamide”. So let’s dive into what ectoin is, what it actually does for the skin, whether or not it can be thought of as a niacinamide replacement...
Read moreExfoliation Treatments: Benefits, How To, and Best Products
Exfoliating skin, sloughing off dead skin cells, buffing out skin roughness, etc. are all concepts that are probably deemed incredibly “old school” and the least glamorous rituals in a skin routine. But experts like us will always give this arena the dedicated spotlight it deserves because it is just that important to skin health. What is Exfoliation? Exfoliation is the act of removing overdue dead skin cells (keratinocytes). Factors like age, climate, and skin diseases can all impact the lev...
Read morePDRN Skincare: Hype vs. Reality
New skincare science is as alluring as it is mysterious. It can often be hard to distinguish between hype and science. But worry not! Let the chemists dissect everything for you. Today, we’re tackling PDRNv—van ingredient that’s been making waves in the beauty world. But what exactly is PDRN, and does it deserve a spot in your routine? Let’s break it down. What is PDRN? PDRN, or polydeoxyribonucleotide, are simply DNA fragments ranging from 50 to 1500 kDa. The concept of using PDRN for therap...
Read moreWhich Vitamin C Derivative is the Best For My Skin?
We have talked about the science behind vitamin C skincare, we have even tested a bunch of CE Ferulic dupes - yet there’s still more for us to cover in the vitamin C serum landscape. Vitamin C is actually a whole family of related molecules that all behave slightly differently. The OG vitamin C with the glitzy skin benefits that you often hear of is L-ascorbic acid. But since ascorbic acid is notoriously unstable in the presence of light, water, and air, many have turned to derivative compoun...
Read moreWe’re Like a Translator For your Skin
Personalize your skincare routine with our modular products. Welcome to scientific skincare without the crazy markup and crazier claims.
Or, Use Our Routine Builder