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LÉ Blog

Vitamin C: The Antioxidant Powerhouse

Vitamin C serums is probably one of the most popular products with countless new launches every year. Their lasting popularity make a lot of sense! Simply put, Vitamin C (specifically ascorbic acid) is one of the most validated actives in the skincare world for its clinical benefits. It has been proven to prevent free radical damage, brighten hyperpigmentation, and even boost collagen production. But given vitamin C’s popularity, it’s only gotten MORE difficult to choose the best vitamin C se...

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What's the deal with CBD serums & oils? - The 2023 edition

Back in fall 2019, we wrote a blog post on CBD in skincare when it was all the rage. During the early days of Covid lockdowns, it really felt like there was a new CBD miracle serum or oil every other week. Even now in spring of 2023, there are still a lot of questions and mystique around this ingredient. So it’s time to revisit CBD and see just what CBD does in skincare, if there are any new clinical studies that have come out on topical CBD, just who might benefit from CBD skincare, and how ...

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A Chemists' Guide to Navigating "Retinol Alternative" Skincare

Retinol’s popularity has only continued to grow in the past few years with no signs of slowing down. And for good reason! Of the actives out there, it comes with quite a resume of data behind it for reducing wrinkles, hyperpigmentation, and even a little acne assistance. However, with that popularity comes a lot of confusion. Choosing the right retinol product can already be complicated, but on top of that, there’s a whole slew of “retinol alternatives” available on the market. In fact, if yo...

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Everything you need to know about silymarin in skincare

There’s an ingredient that's probbbaaabbbly not quite on your skincare radar yet - but we think it’s worth considering. The ingredient is called Silymarin (sih-lee-mae-rin), and comes from the extract of milk thistle. You'll find it on the ingredient list as "Silybum Marianum Fruit Extract", usually in a handful of clinical brands such as Skinceuticals, PCA Skin, and Dr. Dennis Gross…. And most recently our very own Mr. Reliable 2.0! Silymarin is a potent antioxidant with anti-inflammatory pr...

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Our Double Play Retinol Clinical Testing Journey

We always talk a lot about the value of clinical tests in skincare and how helpful they can be in making a purchasing decision. Needless to say, we're doing celebratory dances over here because we finally completed our first clinical, designed with all the bells & whistles that we wanted. After 12 weeks of testing our Double Play Retinol Eye & Face Treatment, we’re excited to finally share the results. This has truly evolved into one of our more elaborate projects that took 2+ years to formul...

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Actives Pairings With Clinical Testing Behind Them

*Updated as of 5/17/2022 When you start dabbling in actives, you’ll easily fall into the rabbit hole of what you can and can’t layer. One of the complicated aspects of trying to figure out actives layering and why brands may not even be able to give clear answers is simply the fact it hasn’t gone through enough testing to truly know. Not to mention, the formulas these actives sit in can add another layer of complexity. The good thing is there are some active combinations that have been looked...

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What's a PHA in Skincare & How to Use

In our final podcast episode of 2021, we dedicated the meat of the episode on a chemical exfoliants update. That’s the alphabet clan of PHAs, AHAs, and BHA, and it resulted in a lot of curiosity about PHAs. Though PHA research is still relatively new and not as well-studied as classic glycolic acid, there’s still some really exciting data that validates it’s use as an exfoliator. In fact, we like gluconolactone so much we use 30% of it in our Baby Steps exfoliating treatment! So let’s do a de...

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The Non-Vitamin C Antioxidants

The summer season is prime time to experiment with the category of antioxidants. All that extra sun means all that potential for photodamage. But all we’ve been talking about here have been very heavily Vitamin C focused, so what about all the other guys you hear about? The Chemist Have to Do Their Annual Rant But wait! What’s this? Another moment for the chemists to moan about the antioxidant category? The definition of antioxidant has truly been dragged through the mud because everything fr...

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How to Combine Skincare Actives like a Pro pt 2

One of our most popular articles of Chemist Confessions and the center of a lot of questions is combining actives. In How to Combine Actives Like a Pro Pt. 1 we shared some tips and tricks on how to combine the big 4 actives of retinol, niacinamide, AHAs, and vitamin C. But what about all the other active ingredients? And what does it all really mean when it comes to product layering? It’s finally time for How to Combine Actives like a pro part 2! *Note: We wrote this for individuals that hav...

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I'm Shopping for Niacinamide! Halp!

So you wanna get some niacinamide into your routine eh? Welp unfortunately in the past couple of years, this category has become quite the circus of products. So let’s take a stroll through the niacinamide landscape and see if we can find your next niacinamide discovery. But Wait! A Quick Recap Before We Explore If you haven’t already, we highly recommend going back to our niacinamide intro to recap what niacinamide can do for your skin. To sum up in one line, niacinamide has shown that with ...

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Matrixyl 3000: an in depth view with Sederma!

Whether you are a skincare newbie or skincare junkie, you’re bound to hear about peptides. It’s that exotic ingredient that shows up in your anti-aging creams and serums that usually comes with a stinging price tag. Yet even for this fancy, seemingly high-tech ingredient category you’ll still have to avoid some duds. The reality is as chemists, you can synthesize a gajillion different peptides out there but very few actually do anything for the skin. So how do you as a consumer know? We proba...

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